Artificial sweeteners can still lead to obesity and diabetes, study claims

'The reality is sick, overweight people with tooth decay'

Researchers said additional studies are needed to further explain the link between artificial sweeteners and obesity and diabetes, and whether they should be avoided.

Despite the fact "most of these sweeteners were approved well before we had the technology to perform studies like my lab is doing", Hoffman said it's only when people "chronically consume" things like artificially-sweetened drinks that people should be concerned.

This new investigation is the biggest examination to date that tracks biochemical changes in the body- utilizing an approach known as impartial high-throughput metabolomics- after utilization of sugar or sugar substitutes. Researchers also looked at the impact of the substances on the lining of blood vessels.

Ever since the artificial sweeteners have been present, people have been alerted about their possible health dangers such as multiple sclerosis and cancer.

The findings, which were presented during the 2018 Experimental Biology meeting held in San Diego, were not the first to suggest artificial sweeteners might have a negative impact on health.

Despite the addition of these non-caloric artificial sweeteners to our everyday diets, there has still been a drastic rise in obesity and diabetes.

To make their findings, the team fed rats diets high in glucose or fructose, both types of sugar, or the common artificial sweeteners aspartame or acesulfame potassium.

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The authors conclude that the vascular changes they observed "may be important during the onset and progression of diabetes and obesity". Following three weeks, the specialists saw noteworthy contrasts in the concentration of amino acids, fats, and biochemicals in blood tests.

Dr Hoffamn said that the research showed that artificial sweeteners posed a health risk after excess consumption.

Also, the sweetener acesulfame potassium was found to slowly build up in the body. But, of course, when it comes to our internal chemistry, nothing is that clear cut.

But a new set of research indicates that the artificial sweeteners bring with them some similar risks of the those very health conditions - but in a different metabolic pathway.

"The negative implications of consuming high amounts of dietary sugar on overall health have always been linked to diabetes, obesity, cardiovascular disease, and other systemic health problems", the authors wrote in a statement.

They injected the cells with the equivalent amount of sweetener seen in someone consuming four cans of diet soda per day and found an increased expression of genes that are markers of fat production and inflammation.

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